ClinicalsMnemonicsTips

Mad as hell ! Medical causes of Anger

I really enjoy conversing with sassy, elderly patients who have lived long enough to be mad at everyone & everything but cope with it with a dash of humor. An elderly patient of mine was very displeased at low-salt lunch she was served after she had ordered food off of a shiny hospital cafe menu and blurted “Wow – The trailer was great, but boy does this movie suck !” 🤣

But I digress, this post is about recalling clues to look for in patients who have become newly irritable and short-tempered in a matter of days, weeks or few months and family is very concerned with the personality change. We rule out potentially treatable, medical or organic causes or anger. Here’s a mnemonic to help recall – Is your angry patient SCREAMING 😡?

SSteroids (can also cause frank psychosis and emotional states), Sundowning (New Dementia coming on ? )
CCalcium elevation
RRecent tragic events (deaths, breakups, new diagnoses, job-loss, etc)
EEpilepsy (non-convulsive or post-ictal confusion/anger) AND Encephalitis (Have seen in 3 cases of CJ-Disease I have seen thus far presenting with angry personality changes, a couple cases of herpes encephalitis presenting with anger & sleepiness and of course there is “Brain on Fire” encephalitis)
AAmmonia elevation
MMedications (including antiseizure, psychiatric and sleeping meds, excess thyroid & statins too)
IIntoxications & Withdrawals (Don’t forget withdrawal from Nicotine & some prescription meds)
NNeoplasms of brain (especially Frontal Lobe)
GGlucose instability with highs and lows. (uncontrolled, too tightly controlled or brittle diabetics)

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